Article
Genetic changes associated with testicular cancer susceptibility.
Seminars in oncology - 1 Oct 2016
Pyle Louise C, Nathanson Katherine L
Abstract excerpt
Testicular germ cell tumor (TGCT) is a highly heritable cancer primarily affecting young white men. Genome-wide association studies (GWAS) have been particularly effective in identifying multiple common variants with strong contribution to TGCT risk. These loci identified through association studies have implicated multiple genes as associated with TGCT predisposition, many of which are unique among cancer types,...
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