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Article

Genetic predisposition to testicular germ-cell tumours.

The Lancet. Oncology - 1 Jun 2004

Lutke Holzik M F, Rapley E A, Hoekstra H J, Sleijfer D T, Nolte I M, Sijmons R H

Abstract excerpt

Testicular germ-cell tumours (TGCT) are the most common neoplasm in young men. Various studies have suggested the existence of an inherited predisposition to development of these tumours. Genome-wide screens subsequently provided evidence of a TGCT susceptibility gene on chromosome Xq27 (TGCT1) that might also predispose to cryptorchism. However, this putative gene has yet to be identified, and other TGCT...

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Identifiers

PMID: 15172357
DOI: 10.1016/S1470-2045(04)01493-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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