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Article

Structural and thermodynamic signatures of DNA recognition by Mycobacterium tuberculosis DnaA.

Journal of molecular biology - 15 Jul 2011

Tsodikov Oleg V, Biswas Tapan

Abstract excerpt

An essential protein, DnaA, binds to 9-bp DNA sites within the origin of replication oriC. These binding events are prerequisite to forming an enigmatic nucleoprotein scaffold that initiates replication. The number, sequences, positions, and orientations of these short DNA sites, or DnaA boxes, within the oriCs of different bacteria vary considerably. To investigate features of DnaA boxes that are important for...

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Identifiers

PMID: 21620858
DOI: 10.1016/j.jmb.2011.05.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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