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Article

Replacement of Mycobacterium smegmatis dnaA gene by Mycobacterium tuberculosis homolog results in temperature sensitivity.

Tuberculosis (Edinburgh, Scotland) - 1 Dec 2011

Madiraju Murty, Madiraju Sai Chandanda, Yamamoto Kohji, Greendyke Rebecca, Rajagopalan Malini

Abstract excerpt

The genetic aspects of DnaA mediated initiation of oriC replication in mycobacteria are largely unknown. To get insights into the replication initiation process in mycobacteria, we characterized Mycobacterium tuberculosis DnaA and its interactions with oriC. We show that the replacement of Mycoba...

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Identifiers

PMID: 22112933
DOI: 10.1016/j.tube.2011.10.023
PMCID: PMC3248996

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22112933-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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