Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene mutations and polymorphisms of TP53 and FHIT in chronic esophagitis and esophageal carcinoma.

Anticancer research - 1 May 2011

Silveira Aparecida Perpetuo Fedossi, Da Silva Manoel-Caetano Fernanda, Aoki Sérgio, Yamasaki Lílian Hiromi Tomonari, Rahal Paula, Silva Ana Elizabete

Abstract excerpt

AIM: The aim of this study was to investigate genetic changes of the TP53 (tumor protein p53) and FHIT (fragile histidine triad) genes in precursor lesion such as chronic esophagitis (CE) and in esophageal squamous cell carcinoma (ESCC). MATERIALS AND METHODS: PCR-Single Strand Conformation Polymorphism (SSCP) analysis and DNA sequencing in 30 CE and 10 ESCC specimens were performed. RESULTS: DNA sequencing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acid Anhydride Hydrolases
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Esophageal Neoplasms

Share to Esophagus

Share to Neoplasm Proteins

Share to Polymorphism, Single-Stranded Conformational

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 21617227

Genes

FHIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene mutations and polymorphisms of TP53 and FHIT in chronic esophagitis and esophageal carcinoma.PMID 21617227Read ↗

Alterations of the TP53 gene in gastric and esophageal carcinogenesis.Semantic proximity Read ↗

Distinct pattern of TP53 mutations in squamous cell carcinoma of the esophagus in Iran.Semantic proximity Read ↗

TP53 Mutations in Esophageal Squamous Cell Carcinoma.Semantic proximity Read ↗

FHIT gene alterations in esophageal cancer and ulcerative colitis (UC).Semantic proximity Read ↗

Mutational profile of TP53 in esophageal squamous cell carcinoma associated with chagasic megaesophagus.Semantic proximity Read ↗

[Association of fragile histidine triad gene (FHIT) with susceptibility to esophageal cancer. A preliminary study].Semantic proximity Read ↗

Frequent inactivation of the TP53 gene in esophageal squamous cell carcinoma from a high-risk population in China.Semantic proximity Read ↗

Common genetic variants of TP53 and BRCA2 in esophageal cancer patients and healthy individuals from low and high risk areas of northern China.Semantic proximity Read ↗

Do FHIT gene alterations play a role in human solid tumors?Semantic proximity Read ↗

Fragile histidine triad gene alterations are not essential for hepatocellular carcinoma development in South Korea.Semantic proximity Read ↗

TP53 gene mutation profile in esophageal squamous cell carcinomas.Semantic proximity Read ↗

Role of p53 gene mutations in human esophageal carcinogenesis: results from immunohistochemical and mutation analyses of carcinomas and nearby non-cancerous lesions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.