Article
Immunodeficiency as primary phenotype of diabetes mutation db. Studies with coxsackievirus B4.
Diabetes - 1 Jun 1990
Montgomery L B, Loria R M, Chinchilli V M
Abstract excerpt
Restriction of food intake (R) in the C57BL/KsJ db/db diabetic mutant mouse prevents phenotypic expression of diabetes, whereas ad libitum feeding (AL) results in spontaneous diabetes. Previous results showed that coxsackievirus B4 (CB4)-infected genetically identical db/db mice with and without diabetes could be distinguished by the levels of CB4-neutralizing antibody and virus-specific antibodies as determined...
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