Immunodeficiency as primary phenotype of diabetes mutation db. Studies with coxsackievirus B4.

doi:10.2337/diab.39.6.675

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Article

Immunodeficiency as primary phenotype of diabetes mutation db. Studies with coxsackievirus B4.

Diabetes - 1 Jun 1990

Montgomery L B, Loria R M, Chinchilli V M

Abstract excerpt

Restriction of food intake (R) in the C57BL/KsJ db/db diabetic mutant mouse prevents phenotypic expression of diabetes, whereas ad libitum feeding (AL) results in spontaneous diabetes. Previous results showed that coxsackievirus B4 (CB4)-infected genetically identical db/db mice with and without...

Topics

Animals
Antibody-Producing Cells
Coxsackievirus Infections
Diabetes Mellitus
Enterovirus B, Human
Enzyme-Linked Immunosorbent Assay
Hemagglutination
Immune Tolerance
Immunization
Lymphocytes
Mice
Mice, Mutant Strains
Phenotype
Spleen

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