Article
Thyroiditis in the BB rat is associated with lymphopenia but occurs independently of diabetes.
Journal of autoimmunity - 1 Aug 1995
Pettersson A, Wilson D, Daniels T, Tobin S, Jacob H J, Lander E S, Lernmark A
Abstract excerpt
The spontaneously diabetic BB rat is an excellent and well studied model for human insulin-dependent diabetes (IDDM), sharing many important features with the human disease. Similarities include an equal frequency of IDDM in males and females, production of antibodies against pancreatic cell anti...
Topics
- Animals
- Chromosome Mapping
- Diabetes Mellitus, Type 1
- Disease Models, Animal
- Disease Susceptibility
- Female
- Genetic Predisposition to Disease
- Genotype
- Histocompatibility Antigens
- Humans
- Lymphopenia
- Major Histocompatibility Complex
- Male
- Rats
- Rats, Inbred BB
- Rats, Inbred F344
- Rats, Inbred Lew
- Risk Factors
