Article
T-lymphocyte requirement for diabetes in RT6-depleted diabetes-resistant BB rats.
Diabetes - 1 Apr 1991
Woda B A, Handler E S, Greiner D L, Reynolds C, Mordes J P, Rossini A A
Abstract excerpt
Diabetes-prone (DP) BB rats develop spontaneous autoimmune insulin-dependent diabetes mellitus (IDDM). The cell populations involved in the expression of diabetes are not precisely known but probably include natural killer (NK) cells, macrophages, and T lymphocytes. Because the DP rat has few lym...
Topics
- ADP Ribose Transferases
- Animals
- Antibodies, Monoclonal
- Antigens, Differentiation
- Antigens, Differentiation, T-Lymphocyte
- Autoimmune Diseases
- CD5 Antigens
- CD8 Antigens
- Diabetes Mellitus, Experimental
- Diabetes Mellitus, Type 1
- Histocompatibility Antigens
- Immunity, Innate
- Lymphocyte Activation
- Lymphocyte Depletion
- Membrane Glycoproteins
- Phenotype
- Rats
- Rats, Inbred BB