Article
Pathophysiology of the pancreas after oral infection of genetically diverse mice with coxsackievirus B4-E2.
Archives of virology - 1 Jan 2015
Precechtelova Jana, Borsanyiova Maria, Stipalova Darina, Sarmirova Sona, Gomolcak Pavol, Berakova Katarina, Bopegamage Shubhada
Abstract excerpt
Coxsackievirus B4 strain E2 (CVB4-E2) and its association with type 1 diabetes (T1D) have been studied in experimental in vitro and in vivo murine models. CVB4-E2, known to be pancreotropic and diabetogenic in nature, is associated with acute pancreatitis in mice but shows differences in the induction of glycemia after intraperitoneal (i.p.) infection. Therefore, the aim of this work was to study the outcome of...
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