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Article

Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and typhoid susceptibility in Asian Malay population in Malaysia.

Microbes and infection - 1 Sept 2011

Bhuvanendran Saatheeyavaane, Hussin Hani M, Meran Lila P, Anthony Amy A, Zhang Leilei, Burch Lauranell H, Phua Kia K, Ismail Asma, Balaram Prabha

Abstract excerpt

Typhoid fever is a major health problem with frequent outbreaks in Kelantan, Malaysia. Prevalence of TLR4 gene polymorphisms varies with ethnic groups (0-20%) and predisposean individual to gram-negative infections. The prevalence rate of TLR4 Asp299Gly and Thr399lle polymorphisms in the Malay population or the influence of these on typhoid fever susceptibility is not yet reported. 250 normal and 304 susceptible...

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Source

Identifiers

PMID: 21612766
DOI: 10.1016/j.micinf.2011.04.007

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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