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Article

Genetic selection pressure in TLR9 gene may enforce risk for SLE in Indian Tamils.

Lupus - 1 Mar 2017

Yusuf J H, Kaliyaperumal D, Jayaraman M, Ramanathan G, Devaraju P

Abstract excerpt

Objectives Lupus is a classical systemic autoimmune disease with genetics as one of the well known causative factors for the disease pathogenesis. Toll-like receptors are the major pattern recognition receptors associated with innate immunity and also act as an interface with the adaptive immunity. Genetic polymorphisms in genes encoding TLRs were implicated in the development of infections, malignancies and...

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Source

Identifiers

PMID: 27432810
DOI: 10.1177/0961203316659151

Genes

TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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