Article
Association of toll-like receptor polymorphisms with susceptibility to chikungunya virus infection.
Virology - 1 Nov 2017
Dutta Sudip Kumar, Tripathi Anusri
Abstract excerpt
Chikungunya virus (CHIKV) infection leads to activation of innate immune response by triggering Toll-like receptor (TLR) pathways resulting in elevated cytokines and type-I interferon levels. Genetic variations of these genes may influence human CHIKV-susceptibility and disease progression. Present study aimed to identify role of TLR polymorphisms in CHIKV-susceptibility and their association with cytokines and...
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