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Article

Association of type I phosphatidylinositol kinase activity with mutationally activated forms of human pp60c-src.

Molecular and cellular biology - 1 Jun 1990

Chan T O, Tanaka A, Bjorge J D, Fujita D J

Abstract excerpt

Chicken embryo fibroblast cells overexpressing activated mutant forms of human pp60c-src, but not those overexpressing normal human pp60c-src, exhibited high levels of type I phosphatidylinositol (PI) kinase activity associated with pp60c-src. Levels of PI kinase activity were positively correlated with src tyrosine protein kinase activity and not with absolute levels of pp60c-src. Our results suggest that a...

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Identifiers

PMID: 2160600
DOI: 10.1128/mcb.10.6.3280-3283.1990
PMCID: PMC360699

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of type I phosphatidylinositol kinase activity with mutationally activated forms of human pp60c-src.PMID 2160600Read ↗

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Autophosphorylation is required for high kinase activity and efficient transformation ability of proteins encoded by host range alleles of v-src.Semantic proximity Read ↗

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