Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential pp60c-src activity in well and poorly differentiated human colon carcinomas and cell lines.

1 Sept 1992

Abstract excerpt

The results presented in this report demonstrate increased pp60c-src kinase activity associated with moderate to well differentiated colon tumors, corroborating previous observations by other groups. Extension of this analysis to include a small number of poorly differentiated colon carcinomas revealed src kinase activity comparable to that observed in normal colonic mucosa, considerably less than that observed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Cancer Screening and Detection
Share to Colorectal Cancer Treatments and Studies
Share to Genetic factors in colorectal cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1381724
DOI: 10.1172/jci115956

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential pp60c-src activity in well and poorly differentiated human colon carcinomas and cell lines.PMID 1381724Read ↗

Activation of the pp60c-src protein kinase is an early event in colonic carcinogenesis.Semantic proximity Read ↗

<i>SRC</i> gene expression in human cancer: the role of transcriptional activationSemantic proximity Read ↗

Activation of c-Src by receptor tyrosine kinases in human colon cancer cells with high metastatic potential.Semantic proximity Read ↗

Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cellsSemantic proximity Read ↗

SRC in human carcinogenesis.Semantic proximity Read ↗

Overexpression of normal c-Src in poorly metastatic human colon cancer cells enhances primary tumor growth but not metastatic potential.Semantic proximity Read ↗

Activation of human pp60c-src.Semantic proximity Read ↗

Activating SRC mutation in a subset of advanced human colon cancers.Semantic proximity Read ↗

Activation of c-Src gene product in hepatocellular carcinoma is highly correlated with the indices of early stage phenotype.Semantic proximity Read ↗

A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer.Semantic proximity Read ↗

Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors.Semantic proximity Read ↗

Expression of pp60c-src in human small cell and non-small cell lung carcinomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.