Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants.

doi:10.1128/mcb.11.2.1107-1113.1991

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Article

Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants.

Molecular and cellular biology - 1 Feb 1991

Varticovski L, Daley G Q, Jackson P, Baltimore D, Cantley L C

Abstract excerpt

A phosphoinositide kinase specific for the D-3 position of the inositol ring, phosphatidylinositol (PI) 3-kinase, associates with activated receptors for platelet-derived growth factor, insulin, and colony-stimulating factor 1, with products of the oncogenes src, fms, yes, crk, and with polyomavi...

Topics

Animals
Cell Line
Cell Membrane
Cell Transformation, Neoplastic
Enzyme Activation
Genes, abl
Genetic Variation
Mice
Oncogene Proteins v-abl
Phosphatidylinositol 3-Kinases
Phosphotransferases

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