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Article

Activation of phosphatidylinositol 3-kinase in cells expressing abl oncogene variants.

Molecular and cellular biology - 1 Feb 1991

Varticovski L, Daley G Q, Jackson P, Baltimore D, Cantley L C

Abstract excerpt

A phosphoinositide kinase specific for the D-3 position of the inositol ring, phosphatidylinositol (PI) 3-kinase, associates with activated receptors for platelet-derived growth factor, insulin, and colony-stimulating factor 1, with products of the oncogenes src, fms, yes, crk, and with polyomavirus middle T antigen. Efficient fibroblast transformation by proteins of the abl and src oncogene families requires...

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Identifiers

PMID: 1846663
DOI: 10.1128/mcb.11.2.1107-1113.1991
PMCID: PMC359788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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