Article
The amino-terminal region of pp60c-src has a modulatory role and contains multiple sites of tyrosine phosphorylation.
Oncogene - 1 Mar 1990
Espino P C, Harvey R, Schweickhardt R L, White G A, Smith A E, Cheng S H
Abstract excerpt
The c-src gene product from either platelet-derived growth factor treated cells or from polyomavirus-infected cells migrates anomalously on gels, displays enhanced kinase activity, and contains additional sites of tyrosine phosphorylation within its amino-terminus. To probe the importance of these post-translational modifications, each of the five amino-terminal tyrosine residues (residues 90, 92, 131, 136, and...
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