Article
Tyrosine phosphorylation of three cellular proteins correlates with transformation of rat 1 cells by pp60src.
Molecular carcinogenesis - 1 Jan 1991
Bouton A H, Kanner S B, Vines R R, Parsons J T
Abstract excerpt
The analysis of phosphotyrosine-containing proteins in Rat 1 cells overexpressing either the tyrosine kinase pp60c-src or genetic variants containing alterations in functional and structural domains has led to the identification of three proteins whose tyrosine phosphorylation correlated with pp60src-induced cellular transformation. The tyrosine phosphorylation of one of these proteins, p120, has been previously...
Topics
- Animals
- Cell Line
- Cell Transformation, Neoplastic
- GTPase-Activating Proteins
- Genes, src
- Genetic Variation
- Molecular Weight
- Mutagenesis
- Peptide Mapping
- Phosphopeptides
- Phosphoproteins