Article
Characterization of hepatitis C Virus genotype 3a hypervariable region 1 in patients achieved rapid virological response to alpha interferon and ribavirin combination therapy.
Virology journal - 23 May 2011
Akram Madiha, Idrees Muhammad, Hussain Abrar, Afzal Samia, Ilyas Muhammad, Zafar Shamail, Aftab Mahwish, Badar Sadaf, Khubaib Bushra
Abstract excerpt
BACKGROUND: Hepatitis C virus roots a chronic liver disease. Currently approved treatment strategy includes administration of alpha interferon and ribavirin combined therapy for 24-48 weeks. One of the predictor of sustained virological response is an early virological response to treatment characterized as rapid response. Hyper variable region 1 (HVR1) of E2 protein is responsible for viral entry and acts as a...
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