Article
Spontaneous clearance of primary acute hepatitis C virus infection correlated with high initial viral RNA level and rapid HVR1 evolution.
Hepatology (Baltimore, Md.) - 1 Jun 2012
Liu Lin, Fisher Brian E, Thomas David L, Cox Andrea L, Ray Stuart C
Abstract excerpt
UNLABELLED: The aim of this study is to determine whether early viral dynamics and evolution predict outcome of primary acute hepatitis C virus (HCV) infection. HCV- and human immunodeficiency virus-negative injection drug users were enrolled prospectively and followed monthly to identify acute HCV infection using RNA detection. Subjects with more than 1 month between HCV-RNA-negative and -positive visits were...
Topics
- Acute Disease
- Adult
- Evolution, Molecular
- Female
- Genotype
- Hepatitis C
- Humans
- Interferons
- Interleukins
- Male
- Prospective Studies
- RNA, Viral