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Article

Susceptibility loci for the defective foreign protein-induced tolerance in New Zealand Black mice: implication of epistatic effects of Fcgr2b and Slam family genes.

European journal of immunology - 1 Aug 2011

Fujii Takuma, Hou Rong, Sato-Hayashizaki Aya, Obata Masaomi, Ohtsuji Mareki, Ikeda Kenichi, Mitsui Kenichi, Kodera Yo, Shirai Toshikazu, Hirose Sachiko, Nishimura Hiroyuki

Abstract excerpt

In contrast to normal mice, autoimmune-prone New Zealand Black (NZB) mice are defective in susceptibility to tolerance induced by deaggregated bovine γ globulin (DBGG). To examine whether this defect is related to the loss of self-tolerance in autoimmunity, susceptibility loci for this defect were examined by genome-wide analysis using the F(2) intercross of nonautoimmune C57BL/6 (B6) and NZB mice. One NZB locus...

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Identifiers

PMID: 21604261
DOI: 10.1002/eji.201141552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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