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Article

Association of extensive polymorphisms in the SLAM/CD2 gene cluster with murine lupus.

Immunity - 1 Dec 2004

Wandstrat Amy E, Nguyen Charles, Limaye Nisha, Chan Alice Y, Subramanian Srividya, Tian Xiang-Hong, Yim Young-Sun, Pertsemlidis Alexander, Garner Harold R, Morel Laurence, Wakeland Edward K

Abstract excerpt

Susceptibility to autoimmunity in B6.Sle1b mice is associated with extensive polymorphisms between two divergent haplotypes of the SLAM/CD2 family of genes. The B6.Sle1b-derived SLAM/CD2 family haplotype is found in many other laboratory mouse strains but only causes autoimmunity in the context of the C57Bl/6 (B6) genome. Phenotypic analyses have revealed variations in the structure and expression of several...

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Identifiers

PMID: 15589166
DOI: 10.1016/j.immuni.2004.10.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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