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Article

RNA polymerase II kinetics in polo polyadenylation signal selection.

The EMBO journal - 20 May 2011

Pinto Pedro A B, Henriques Telmo, Freitas Marta O, Martins Torcato, Domingues Rita G, Wyrzykowska Paulina S, Coelho Paula A, Carmo Alexandre M, Sunkel Claudio E, Proudfoot Nicholas J, Moreira Alexandra

Abstract excerpt

Regulated alternative polyadenylation is an important feature of gene expression, but how gene transcription rate affects this process remains to be investigated. polo is a cell-cycle gene that uses two poly(A) signals in the 3' untranslated region (UTR) to produce alternative messenger RNAs that differ in their 3'UTR length. Using a mutant Drosophila strain that has a lower transcriptional elongation rate, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21602789
DOI: 10.1038/emboj.2011.156
PMCID: PMC3116286

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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