Article
Alternative splicing and expressivity of the Axin(Fu) allele in mice.
Heredity - 1 Aug 2001
Flood W D, Ruvinsky A
Abstract excerpt
Variable expressivity and incomplete penetrance are common for numerous mutations. In most cases the reasons behind these phenomena remain obscure. Caused by the insertion of a murine retrotransposon into intron 6 of the Axin locus, the Axin(Fu) mutation induces alternative splicing and ultimately leads to abnormal tail development in mice. In this investigation RNase protection assay was used to investigate the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
