Association between the TPH1 A218C polymorphism and risk of mood disorders and alcohol dependence: evidence from the current studies.

doi:10.1016/j.jad.2011.04.018

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Article

Association between the TPH1 A218C polymorphism and risk of mood disorders and alcohol dependence: evidence from the current studies.

Journal of affective disorders - 1 Apr 2012

Chen Dingyan, Liu Fang, Yang Chengwu, Liang Xunchang, Shang Qinggang, He Wulong, Wang Zengzhen

Abstract excerpt

BACKGROUND: Several studies have assessed the association between genetic polymorphisms of tryptophan hydroxylase (TPH1) and risk of mood disorders and alcohol dependence, with controversial results. Our aim was to assess the association of TPH1 A218C polymorphism (rs1800532) with mood disorders, including major depressive disorder and bipolar disorder, and alcohol dependence by using meta-analysis. METHODS: Data...

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Identifiers

PMID: 21601290
DOI: 10.1016/j.jad.2011.04.018

Genes

TPH1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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