Article
A genetic perspective on coeliac disease.
Trends in molecular medicine - 1 Nov 2010
Trynka Gosia, Wijmenga Cisca, van Heel David A
Abstract excerpt
Coeliac disease is an inflammatory disorder of the small intestine with an autoimmune component and strong heritability. Genetic studies have confirmed strong association to HLA and identified 39 nonHLA risk genes, mostly immune-related. Over 50% of the disease-associated single nucleotide polymo...
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