Article
A genetic perspective on coeliac disease.
Trends in molecular medicine - 1 Nov 2010
Trynka Gosia, Wijmenga Cisca, van Heel David A
Abstract excerpt
Coeliac disease is an inflammatory disorder of the small intestine with an autoimmune component and strong heritability. Genetic studies have confirmed strong association to HLA and identified 39 nonHLA risk genes, mostly immune-related. Over 50% of the disease-associated single nucleotide polymorphisms are correlated with gene expression. Most of the coeliac disease-associated regions are shared with other...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
