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Article

Expression analysis in intestinal mucosa reveals complex relations among genes under the association peaks in celiac disease.

European journal of human genetics : EJHG - 1 Aug 2015

Plaza-Izurieta Leticia, Fernandez-Jimenez Nora, Irastorza Iñaki, Jauregi-Miguel Amaia, Romero-Garmendia Irati, Vitoria Juan Carlos, Bilbao Jose Ramon

Abstract excerpt

Celiac disease is a chronic immune-mediated disorder with an important genetic component. To date, there are 57 independent association signals from 39 non-HLA loci, and a total of 66 candidate genes have been proposed. We aimed to scrutinize the functional implication of 45 of those genes by analyzing their expression in the disease tissue of celiac patients (at diagnosis/treatment) compared with non-celiac...

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Identifiers

PMID: 25388004
DOI: 10.1038/ejhg.2014.244
PMCID: PMC4795102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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