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Article

Combined functional and positional gene information for the identification of susceptibility variants in celiac disease.

Gastroenterology - 1 Mar 2008

Castellanos-Rubio Ainara, Martin-Pagola Ainhoa, Santín Izortze, Hualde Idoia, Aransay Ana María, Castaño Luis, Vitoria Juan Carlos, Bilbao Jose Ramon

Abstract excerpt

BACKGROUND & AIMS: Celiac disease is a complex, immune-mediated disorder of the intestinal mucosa with a strong genetic component. HLA-DQ2 is the major determinant of risk, but other minor genes, still to be identified, also are involved. METHODS: We designed a strategy that combines gene expression profiling of intestinal biopsy specimens, linkage region information, and different bioinformatics tools for the...

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Source

Identifiers

PMID: 18241860
DOI: 10.1053/j.gastro.2007.11.041

Genes

PBX3
SERPINE2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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