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Article

Amplification of polyomavirus DNA sequences stably integrated in rat cells.

Nucleic acids research - 11 Dec 1991

St-Onge L, Bastin M

Abstract excerpt

To investigate the mechanism by which the polyomavirus large T antigen (T-Ag) promotes amplification of integrated viral sequences, we constructed a rat cell line, Hy2-ts5, carrying two different inserts of polyomavirus DNA. The first insert, designated the middle T (pmt) locus, was devised to analyze homologous recombination between two defective copies of pmt lying 3.3 kb apart on the same chromosome....

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Identifiers

PMID: 1661409
DOI: 10.1093/nar/19.23.6619
PMCID: PMC329231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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