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Article

Intrachromosomal recombination mediated by the polyomavirus large T antigen.

Virology - 10 Jan 1995

Laurent S, Frances V, Bastin M

Abstract excerpt

We used a spleen necrosis virus-based retroviral vector to introduce the polyomavirus replication origin into rat cells and developed a system to analyze homologous recombination events that do not reconstitute a selectable marker. Introduction of the gene coding for the polyomavirus large T antigen into the cell lines by DNA transfection promoted high-frequency recombination between the two retroviral LTRs,...

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Identifiers

PMID: 7831777
DOI: 10.1016/s0042-6822(95)80037-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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