Intrachromosomal recombination mediated by the polyomavirus large T antigen.

doi:10.1016/s0042-6822(95)80037-9

Back to search

Article

Intrachromosomal recombination mediated by the polyomavirus large T antigen.

Virology - 10 Jan 1995

Laurent S, Frances V, Bastin M

Abstract excerpt

We used a spleen necrosis virus-based retroviral vector to introduce the polyomavirus replication origin into rat cells and developed a system to analyze homologous recombination events that do not reconstitute a selectable marker. Introduction of the gene coding for the polyomavirus large T anti...

Topics

Animals
Antigens, Polyomavirus Transforming
Base Sequence
Cell Line
Chromosomes
DNA
Gene Rearrangement
Molecular Sequence Data
Mutation
Polyomavirus
Rats
Recombination, Genetic
Replication Origin

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.