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Article

Persistent induction of cyclooxygenase in p60v-src-transformed 3T3 fibroblasts.

Proceedings of the National Academy of Sciences of the United States of America - 1 May 1990

Han J W, Sadowski H, Young D A, Macara I G

Abstract excerpt

A BALB/c 3T3 cell line infected with the temperature-sensitive Rous sarcoma virus strain LA90 has been used to investigate early, p60v-src-dependent changes in gene expression (protein synthesis). Giant two-dimensional electrophoresis, which can resolve greater than 3000 polypeptides from [35S]methionine-labeled cell lysates, was used to detect the induction of a p72-74 (72-74 kDa) doublet (pI 7.5) after...

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Identifiers

PMID: 2159148
DOI: 10.1073/pnas.87.9.3373
PMCID: PMC53902

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Persistent induction of cyclooxygenase in p60v-src-transformed 3T3 fibroblasts.PMID 2159148Read ↗

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