Article
The oncogenic protein p60v-src has competence activity but does not activate phosphatidylinositol turnover or protein kinase C in Balb/c 3T3 cells.
Oncogene - 1 Apr 1990
Han J W, Gaut J, Burstein E, Sadowski H, Young D, Macara I G
Abstract excerpt
A Balb/c 3T3 cell-line infected with the temperature-sensitive Rous sarcoma virus LA90 has been used to investigate the mitogenic activity of p60v-src and the possible role of phosphatidylinositol turnover and protein kinase C activation in this process. Activation of the p60v-src tyrosine kinase alone was only weakly mitogenic to serum-deprived cells. However, transient activation of the kinase dramatically...
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