Article
The oncogenic protein p60v-src has competence activity but does not activate phosphatidylinositol turnover or protein kinase C in Balb/c 3T3 cells.
Oncogene - 1 Apr 1990
Han J W, Gaut J, Burstein E, Sadowski H, Young D, Macara I G
Abstract excerpt
A Balb/c 3T3 cell-line infected with the temperature-sensitive Rous sarcoma virus LA90 has been used to investigate the mitogenic activity of p60v-src and the possible role of phosphatidylinositol turnover and protein kinase C activation in this process. Activation of the p60v-src tyrosine kinase...
Topics
- Animals
- Avian Sarcoma Viruses
- Cell Division
- Cell Transformation, Neoplastic
- Cells, Cultured
- Enzyme Activation
- Inositol
- Inositol Phosphates
- Kinetics
- Mice
- Mice, Inbred BALB C
- Mutation
- Oncogene Protein pp60(v-src)
- Phosphatidylinositols
- Protein Kinase C
- Proto-Oncogene Proteins
- Signal Transduction
- Temperature