Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

XCI in preimplantation mouse and human embryos: first there is remodelling…

6 Jun 2011

Abstract excerpt

Female eutherians silence one of their X chromosomes to accomplish an equal dose of X-linked gene expression compared with males. The mouse is the most widely used animal model in XCI research and has proven to be of great significance for understanding the complex mechanism of X-linked dosage compensation. Although the basic principles of XCI are similar in mouse and humans, differences exist in the timing of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21647603
DOI: 10.1007/s00439-011-1014-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

XCI in preimplantation mouse and human embryos: first there is remodelling…PMID 21647603Read ↗

Evolutionary origins and chromatin state shape X-chromosome upregulation pattern during eutherian and metatherian embryogenesisSemantic proximity Read ↗

X-chromosome dosage compensation dynamics in human early embryosSemantic proximity Read ↗

Understanding the X chromosome inactivation cycle in miceSemantic proximity Read ↗

Epigenetic regulation of X-inactivation in human embryonic stem cells.Semantic proximity Read ↗

Regulation of X-chromosome inactivation by the X-inactivation centre.Semantic proximity Read ↗

X-chromosome inactivation and its implications for human diseaseSemantic proximity Read ↗

Mechanistic diversification of <i>XIST</i> regulatory network in mammalsSemantic proximity Read ↗

X-factors in human disease: impact of gene content and dosage regulation.Semantic proximity Read ↗

Cross-species comparison of mouse and human preimplantation development with an emphasis on lineage specificationSemantic proximity Read ↗

XIST expression from the maternal X chromosome in human male preimplantation embryos at the blastocyst stageSemantic proximity Read ↗

Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during developmentSemantic proximity Read ↗

Epigenetic reprogramming throughout preimplantation development and consequences for assisted reproductive technologiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.