Molecular mechanisms of replicational fidelity in Escherichia coli.

doi:10.1007/978-1-4615-9561-8_25

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Article

Molecular mechanisms of replicational fidelity in Escherichia coli.

Basic life sciences - 1 Jan 1990

Maki H, Akiyama M, Horiuchi T, Sekiguchi M

Abstract excerpt

DNA polymerase III holoenzyme is responsible for chromosomal DNA synthesis in Escherichia coli and seems to be a major determinant of the fidelity of replication of this organism. Among ten different subunits of the holoenzyme, the alpha subunit, encoded by the dnaE gene, has a polymerase activit...

Topics

Bacterial Proteins
Base Composition
DNA Polymerase III
DNA Replication
DNA, Bacterial
Deoxyribonucleotides
Escherichia coli
Escherichia coli Proteins
Mutation
Phosphoric Monoester Hydrolases
Pyrophosphatases

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