Article
DNA polymerase II as a fidelity factor in chromosomal DNA synthesis in Escherichia coli.
Molecular microbiology - 1 Oct 2005
Banach-Orlowska Magdalena, Fijalkowska Iwona J, Schaaper Roel M, Jonczyk Piotr
Abstract excerpt
Escherichia coli DNA polymerase III holoenzyme (HE) is the main replicase responsible for replication of the bacterial chromosome. E. coli contains four additional polymerases, and it is a relevant question whether these might also contribute to chromosomal replication and its fidelity. Here, we have investigated the role of DNA polymerase II (Pol II) (polB gene product). Mismatch repair-defective strains...
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