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Article

Genetic and in vitro assays of DNA deamination.

Methods in enzymology - 1 Jan 2006

Coker Heather A, Morgan Hugh D, Petersen-Mahrt Svend K

Abstract excerpt

The DNA deaminase family encompasses enzymes that have been highly conserved throughout vertebrate evolution and which display wide-ranging positive effects upon innate and adaptive immune system and development. Activation-induced cytidine deaminase was identified as a DNA mutator after its necessity in the successful development of high-affinity B cells via somatic hypermutation, class switch recombination, and...

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Identifiers

PMID: 16793368
DOI: 10.1016/S0076-6879(06)08010-4

Genes

APOBEC1
APOBEC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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