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Article

Frequencies of SLC44A2 alleles encoding human neutrophil antigen‐3 variants in the African American population

1 Nov 2011

Abstract excerpt

BACKGROUND: The human neutrophil antigen-3 (HNA-3) epitopes reside on the choline transporter-like protein-2 (CTL2). A single-nucleotide substitution (461G>A; Arg154Gln) on the CTL2 gene (SLC44A2) defines the allele SLC44A2*1, which expresses HNA-3a, and SLC44A2*2, which expresses HNA-3b; an additional substitution (457C>T; Leu153Phe) in SLC44A2*1:2 may impact genotyping systems. People who only express HNA-3b...

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PMID: 22040064
DOI: 10.1111/j.1537-2995.2011.03396.x

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