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Article

Digesting the genetics of inflammatory bowel disease: insights from studies of autophagy risk genes.

Inflammatory bowel diseases - 1 Apr 2012

Kabi Amrita, Nickerson Kourtney P, Homer Craig R, McDonald Christine

Abstract excerpt

The success of genetic analyses identifying multiple loci associated with inflammatory bowel disease (IBD) susceptibility has resulted in the identification of several risk genes linked to a common cellular process called autophagy. Autophagy is a process involving the encapsulation of cytosolic cellular components in double-membrane vesicles, their subsequent lysosomal degradation, and recycling of the degraded...

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Identifiers

PMID: 21936032
DOI: 10.1002/ibd.21868
PMCID: PMC3245781

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Source receipt: pubmed, retrieved 7 Sept 2026.

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