Article
Zinc finger recombinases with adaptable DNA sequence specificity.
PloS one - 29 Apr 2011
Proudfoot Chris, McPherson Arlene L, Kolb Andreas F, Stark W Marshall
Abstract excerpt
Site-specific recombinases have become essential tools in genetics and molecular biology for the precise excision or integration of DNA sequences. However, their utility is currently limited to circumstances where the sites recognized by the recombinase enzyme have been introduced into the DNA being manipulated, or natural 'pseudosites' are already present. Many new applications would become feasible if...
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