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Article

Genome targeting by hybrid Flp-TAL recombinases.

Scientific reports - 15 Oct 2020

Voziyanova Eugenia, Li Feng, Shah Riddhi, Voziyanov Yuri

Abstract excerpt

Genome engineering is a rapidly evolving field that benefits from the availability of different tools that can be used to perform genome manipulation tasks. We describe here the development of the Flp-TAL recombinases that can target genomic FRT-like sequences in their native chromosomal locations. Flp-TAL recombinases are hybrid enzymes that are composed of two functional modules: a variant of site-specific...

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Identifiers

PMID: 33060660
DOI: 10.1038/s41598-020-74474-2
PMCID: PMC7562724

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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