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Article

Multiplexing RMCE: versatile extensions of the Flp-recombinase-mediated cassette-exchange technology.

Journal of molecular biology - 10 Sept 2010

Turan Soeren, Kuehle Johannes, Schambach Axel, Baum Christopher, Bode Juergen

Abstract excerpt

There are strong indications, but as yet no proof, that extended 48-bp Flp recombinase targets (FRTs) represent unique targets in all eukaryotic genomes investigated, and that recombinase-mediated cassette exchange is not hampered by the occurrence of genomic pseudo sites. This encouraged the present study in which we explore the feasibility of exchanging, in a given cell, two distinct genomically anchored...

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PMID: 20650281
DOI: 10.1016/j.jmb.2010.07.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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