Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levels.

Journal of biomedical science - 8 Jun 2009

Aigner Bernhard, Rathkolb Birgit, Klempt Martina, Wagner Sibylle, Michel Dian, de Angelis Martin Hrabé, Wolf Eckhard

Abstract excerpt

BACKGROUND: Clinical chemical blood analysis including plasma electrolytes is routinely carried out for the diagnosis of various organ diseases. Phenotype-driven N-ethyl-N-nitrosourea (ENU) mouse mutagenesis projects used plasma electrolytes as parameters for the generation of novel animal models for human diseases. METHODS: Here, we retrospectively evaluated the use of the plasma electrolytes calcium, chloride,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alkylating Agents
Share to Calcium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chlorides

Share to Electrolytes

Share to Ethylnitrosourea

Share to Mice, Inbred C3H

Share to Potassium

Share to Sodium

Source

Open in PubMed Open full text

Identifiers

PMID: 19505327
DOI: 10.1186/1423-0127-16-53
PMCID: PMC2697975

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levels.PMID 19505327Read ↗

Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models.Semantic proximity Read ↗

Screening for increased plasma urea levels in a large-scale ENU mouse mutagenesis project reveals kidney disease models.Semantic proximity Read ↗

Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters.Semantic proximity Read ↗

ENU-induced phenovariance in mice: inferences from 587 mutations.Semantic proximity Read ↗

Mouse ENU mutagenesis.Semantic proximity Read ↗

The clinical-chemical screen in the Munich ENU Mouse Mutagenesis Project: screening for clinically relevant phenotypes.Semantic proximity Read ↗

Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels.Semantic proximity Read ↗

ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level.Semantic proximity Read ↗

Novel phenotypes identified by plasma biochemical screening in the mouse.Semantic proximity Read ↗

ENU mutagenesis in the mouse: application to human genetic disease.Semantic proximity Read ↗

Genome-wide analysis of chemically induced mutations in mouse in phenotype-driven screens.Semantic proximity Read ↗

ENU-based phenotype-driven screening.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.