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Article

A novel ENU-induced Cpox mutation causes microcytic hypochromic anemia in mice.

Experimental animals - 10 Nov 2022

Miyasaka Yuki, Okuda Kento, Miura Ikuo, Motegi Hiromi, Wakana Shigeharu, Ohno Tamio

Abstract excerpt

Mouse models of red blood cell abnormalities are important for understanding the underlying molecular mechanisms of human erythrocytic diseases. DBA.B6-Mha (Microcytic hypochromic anemia) congenic mice were generated from the cross between N-ethyl-N-nitrosourea (ENU)-mutagenized male C57BL/6J and female DBA/2J mice as part of the RIKEN large-scale ENU mutagenesis project. The mice were established by backcrossing...

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Identifiers

PMID: 35527013
DOI: 10.1538/expanim.22-0032
PMCID: PMC9671764

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