Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels.

doi:10.1007/s10534-015-9824-1

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Article

Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine - 1 Apr 2015

Rathkolb Birgit, Klempt Martina, Sabrautzki Sibylle, Michel Dian, Klaften Matthias, Laufs Jürgen, Sedlmeier Reinhard, Hans Wolfgang, Fuchs Helmut, Muckenthaler Martina U, Horsch Marion, Campagna Dean R, Fleming Mark, Hrabé de Angelis Martin, Wolf Eckhard, Aigner Bernhard

Abstract excerpt

Iron is essential for numerous cellular processes. For diagnostic purposes iron-related parameters in patients are assessed by clinical chemical blood analysis including the analysis of ferritin, transferrin and iron levels. Here, we retrospectively evaluated the use of these parameters in the phenotype-driven Munich N-ethyl-N-nitrosourea mouse mutagenesis project for the generation of novel animal models for...

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PMID: 25636453
DOI: 10.1007/s10534-015-9824-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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