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Article

Neuronal transcriptome analyses reveal novel neuropeptide modulators of excitation and inhibition imbalance in C. elegans.

PloS one - 1 Jan 2020

McCulloch Katherine A, Zhou Kingston, Jin Yishi

Abstract excerpt

Neuropeptides are secreted molecules that have conserved roles modulating many processes, including mood, reproduction, and feeding. Dysregulation of neuropeptide signaling is also implicated in neurological disorders such as epilepsy. However, much is unknown about the mechanisms regulating specific neuropeptides to mediate behavior. Here, we report that the expression levels of dozens of neuropeptides are...

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PMID: 32497060
DOI: 10.1371/journal.pone.0233991
PMCID: PMC7272019

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