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Article

The mode of action of a nitroconjugated neonicotinoid and the effects of target site mutation Y151S on its potency.

Insect biochemistry and molecular biology - 1 Jul 2011

Shao Xusheng, Lu Haiyan, Bao Haibo, Xu Xiaoyong, Liu Zewen, Li Zhong

Abstract excerpt

Neonicotinoid insecticides, such as imidacloprid, are selective agonists of the insect nicotinic acetylcholine receptors (nAChRs) with -NO(2) or -CN group in trans-configuration. Previously we reported the excellent insecticidal activity of a series of nitroconjugated neonicotinoids with -NO(2) or -CN group in cis-configuration by replacing nitromethylene pharmacophore with a nitroconjugated system. To understand...

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PMID: 21549193
DOI: 10.1016/j.ibmb.2011.04.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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