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Article

Quantitative detection of HIV-1 drug resistance mutations by automated DNA sequencing.

Nature - 14 Oct 1993

Larder B A, Kohli A, Kellam P, Kemp S D, Kronick M, Henfrey R D

Abstract excerpt

A comparison has been made between manual and automated DNA sequencing procedures to evaluate the ability to distinguish mixtures of wild-type and mutant sequences. Quantitative detection of such mixtures of HIV-1 drug resistance mutations was best achieved using an automated system that uses flu...

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PMID: 8413632
DOI: 10.1038/365671a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8413632-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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