Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MinVar: A rapid and versatile tool for HIV-1 drug resistance genotyping by deep sequencing.

Journal of virological methods - 1 Feb 2017

Huber Michael, Metzner Karin J, Geissberger Fabienne D, Shah Cyril, Leemann Christine, Klimkait Thomas, Böni Jürg, Trkola Alexandra, Zagordi Osvaldo

Abstract excerpt

Genotypic monitoring of drug-resistance mutations (DRMs) in HIV-1 infected individuals is strongly recommended to guide selection of the initial antiretroviral therapy (ART) and changes of drug regimens. Traditionally, mutations conferring drug resistance are detected by population sequencing of the reverse transcribed viral RNA encoding the HIV-1 enzymes target by ART, followed by manual analysis and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to HIV Infections

Share to INDEL Mutation

Share to Microbial Sensitivity Tests

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 27867045
DOI: 10.1016/j.jviromet.2016.11.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MinVar: A rapid and versatile tool for HIV-1 drug resistance genotyping by deep sequencing.PMID 27867045Read ↗

G-HIV: An Integrated Long-Read Sequencing and Automated Bioinformatics Platform for Rapid and Precise HIV-1 SurveillanceSemantic proximity Read ↗

HIV-DRIVES: HIV Drug Resistance Identification, Variant Evaluation, & Surveillance PipelineSemantic proximity Read ↗

Deep sequencing for HIV-1 clinical management.Semantic proximity Read ↗

Direct whole-genome sequencing of HIV-1 for clinical drug-resistance analysis and public health surveillance.Semantic proximity Read ↗

HIV-DRIVES: HIV Drug Resistance Identification, Variant Evaluation, & Surveillance PipelineSemantic proximity Read ↗

Deep sequencing of HIV: clinical and research applications.Semantic proximity Read ↗

Sensitive HIV-1 DNA Pol Next-Generation Sequencing for the Characterisation of Archived Antiretroviral Drug Resistance.Semantic proximity Read ↗

Prevalence of HIV-1 drug resistance mutations in proviral DNA in the Swiss HIV Cohort Study, a retrospective study from 1995 to 2018.Semantic proximity Read ↗

Technologies for HIV-1 drug resistance testing: inventory and needs.Semantic proximity Read ↗

A Comprehensive Genomics Solution for HIV Surveillance and Clinical Monitoring in Low-Income SettingsSemantic proximity Read ↗

Performance comparison of deep sequencing platforms for detecting HIV-1 variants in the pol gene.Semantic proximity Read ↗

Comparison of ultra-deep versus Sanger sequencing detection of minority mutations on the HIV-1 drug resistance interpretations after virological failureSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.