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Article

Phenotypic and genotypic HIV-1 drug resistance assays provide complementary information.

Journal of acquired immune deficiency syndromes (1999) - 1 Oct 2002

Parkin Neil, Chappey Colombe, Maroldo Laura, Bates Michael, Hellmann Nicholas S, Petropoulos Christos J

Abstract excerpt

To determine the extent to which genotype (GT) or phenotype (PT) methods provide HIV-1 drug resistance information that is overlapping or complementary, both tests were performed on 1378 patient plasma samples. Discordance, defined as determination of reduced susceptibility measured by PT but sensitivity by GT (PT-R/GT-S), or vice versa (PT-S/GT-R), was common: 83, 62, 43, and 28% of samples with evidence of drug...

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Identifiers

PMID: 12394790
DOI: 10.1097/00126334-200210010-00002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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