Article
Exploiting genome structure in association analysis.
Journal of computational biology : a journal of computational molecular cell biology - 1 Apr 2014
Kim Seyoung, Xing Eric P
Abstract excerpt
A genome-wide association study involves examining a large number of single-nucleotide polymorphisms (SNPs) to identify SNPs that are significantly associated with the given phenotype, while trying to reduce the false positive rate. Although haplotype-based association methods have been proposed to accommodate correlation information across nearby SNPs that are in linkage disequilibrium, none of these methods...
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