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Article

Role of the polycomb group gene BMI1 in normal and leukemic hematopoietic stem and progenitor cells.

Current opinion in hematology - 1 Jul 2010

Schuringa Jan J, Vellenga Edo

Abstract excerpt

PURPOSE OF REVIEW: The polycomb group gene BMI1 fulfills essential roles in both normal and leukemic stem cells. The underlying molecular mechanisms are beginning to become unraveled and an overview of the current knowledge on BMI1 signaling in normal and leukemic stem cells will be presented here. RECENT FINDINGS: In addition to a role in bypassing senescence and the orchestration of the symmetry of...

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Source

Identifiers

PMID: 20308890
DOI: 10.1097/MOH.0b013e328338c439

Genes

BMI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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